Centre for Experimental Biophysical Chemistry

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  • Currently displaying 201 - 220 of 1115 publications
Author(s)
Publication title
Journal Name
Publication year
Microfluidics for multiscale studies of biomolecular condensates
NA Erkamp, R Qi, TJ Welsh, TPJ Knowles
Lab on a chip
(2022)
23
(doi: 10.1039/d2lc00622g)
Selenium Silk Nanostructured Films for Antifungal and Antibacterial Treatments
Z Toprakcioglu, E Wiita, A Jayaram, R Gregory, T Knowles
(2022)
(doi: 10.1101/2022.12.18.520325)
The Chromatin Regulator HMGA1a Undergoes Phase Separation in the Nucleus.
H Zhu, M Narita, JA Joseph, G Krainer, WE Arter, I Olan, KL Saar, N Ermann, JR Espinosa, Y Shen, MA Kuri, R Qi, TJ Welsh, R Collepardo-Guevara, M Narita, TPJ Knowles
Chembiochem : a European journal of chemical biology
(2022)
24
(doi: 10.1002/cbic.202200450)
Core-Shell Spheroid-Laden Microgels Crosslinked under Biocompatible Conditions for Probing Cancer-Stromal Communication
H Zhu, LWY Roode, AJ Parry, NA Erkamp, M Rodriguez-Garcia, M Narita, Y Shen, Y Ou, Z Toprakcioglu, M Narita, TPJ Knowles
Advanced Nanobiomed Research
(2022)
2
(doi: 10.1002/anbr.202200138)
Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration
S Fiedler, SRA Devenish, AS Morgunov, A Ilsley, F Ricci, M Emmenegger, V Kosmoliaptsis, ES Theel, JR Mills, AM Sholukh, A Aguzzi, A Iwasaki, AK Lynn, TPJ Knowles
Sci Rep
(2022)
12
(doi: 10.1038/s41598-022-22214-z)
Structure-Based Discovery of Small-Molecule Inhibitors of the Autocatalytic Proliferation of α‑Synuclein Aggregates
S Chia, Z Faidon Brotzakis, RI Horne, A Possenti, B Mannini, R Cataldi, M Nowinska, R Staats, S Linse, TPJ Knowles, J Habchi, M Vendruscolo
Molecular pharmaceutics
(2022)
20
(doi: 10.1021/acs.molpharmaceut.2c00548)
Non-specificity as the sticky problem in therapeutic antibody development.
H Ausserwöger, MM Schneider, TW Herling, P Arosio, G Invernizzi, TPJ Knowles, N Lorenzen
Nat Rev Chem
(2022)
6
(doi: 10.1038/s41570-022-00438-x)
Microscale Diffusiophoresis of Proteins
QAE Peter, RPB Jacquat, TW Herling, PK Challa, T Kartanas, TPJ Knowles
Journal of Physical Chemistry B
(2022)
126
(doi: 10.1021/acs.jpcb.2c04029)
Multi-dimensional protein solubility optimization with an ultra-high-throughput microfluidic platform
N Erkamp, M Oeller, T Sneideris, H Ausserwӧger, A Levin, T Welsh, R Qi, D Qian, H Zhu, P Sormanni, M Vendruscolo, TPJ Knowles
(2022)
(doi: 10.1101/2022.10.21.513267)
Author Correction: Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity (Nature Neuroscience, (2022), 25, 9, (1134-1148), 10.1038/s41593-022-01140-3)
ML Choi, A Chappard, BP Singh, C Maclachlan, M Rodrigues, EI Fedotova, AV Berezhnov, S De, CJ Peddie, D Athauda, GS Virdi, W Zhang, JR Evans, AI Wernick, ZS Zanjani, PR Angelova, N Esteras, AY Vinokurov, K Morris, K Jeacock, L Tosatto, D Little, P Gissen, DJ Clarke, T Kunath, L Collinson, D Klenerman, AY Abramov, MH Horrocks, S Gandhi
Nature neuroscience
(2022)
25
(doi: 10.1038/s41593-022-01206-2)
Characterization of full-length p53 aggregates and their kinetics of formation
L Julian, JC Sang, Y Wu, G Meisl, JH Brelstaff, A Miller, MR Cheetham, M Vendruscolo, TPJ Knowles, FS Ruggeri, C Bryant, S Ros, KM Brindle, D Klenerman
Biophys J
(2022)
121
(doi: 10.1016/j.bpj.2022.10.013)
Intracellular FUS protein accumulation leads to cytoskeletal, organelle and cellular homeostasis perturbations
CW Chung, A Zhou, I Mela, A Stephens, A Miyashita, P St George-Hyslop, C Kaminski, T Knowles, G Kaminski Schierle
(2022)
(doi: 10.1101/2022.10.04.510756)
Hydrodynamics of Droplet Sorting in Asymmetric Acute Junctions.
H Yang, TPJ Knowles
Micromachines (Basel)
(2022)
13
(doi: 10.3390/mi13101640)
An antibody scanning method for the detection of α-synuclein oligomers in the serum of Parkinson's disease patients
K Kulenkampff, D Emin, R Staats, YP Zhang, L Sakhnini, A Kouli, O Rimon, E Lobanova, CH Williams-Gray, FA Aprile, P Sormanni, D Klenerman, M Vendruscolo
Chemical Science
(2022)
13
(doi: 10.1039/d2sc00066k)
Influence of denaturants on amyloid β42 aggregation kinetics.
T Weiffert, G Meisl, S Curk, R Cukalevski, A Šarić, TPJ Knowles, S Linse
Frontiers in Neuroscience
(2022)
16
(doi: 10.3389/fnins.2022.943355)
Small soluble α-synuclein aggregates are the toxic species in Parkinson's disease.
D Emin, YP Zhang, E Lobanova, A Miller, X Li, Z Xia, H Dakin, DI Sideris, JYL Lam, RT Ranasinghe, A Kouli, Y Zhao, S De, TPJ Knowles, M Vendruscolo, FS Ruggeri, FI Aigbirhio, CH Williams-Gray, D Klenerman
Nature Communications
(2022)
13
(doi: 10.1038/s41467-022-33252-6)
Small soluble α-synuclein aggregates are the toxic species in Parkinson’s disease
D Emin, YP Zhang, E Lobanova, A Miller, X Li, Z Xia, H Dakin, DI Sideris, JYL Lam, RT Ranasinghe, A Kouli, Y Zhao, S De, TPJ Knowles, M Vendruscolo, FS Ruggeri, FI Aigbirhio, CH Williams-Gray, D Klenerman
Nature Communications
(2022)
13
(doi: 10.1038/s41467-022-33252-6)
A chip-based supersonic microfluidic nebulizer for efficient sample introduction into inductively coupled plasma – Mass spectrometry
E Mavrakis, Z Toprakcioglu, N Lydakis-Simantiris, TPJ Knowles, SA Pergantis
Analytica chimica acta
(2022)
1229
(doi: 10.1016/j.aca.2022.340342)
Pathological structural conversion of α-synuclein at the mitochondria induces neuronal toxicity
ML Choi, A Chappard, BP Singh, C Maclachlan, M Rodrigues, EI Fedotova, AV Berezhnov, S De, CJ Peddie, D Athauda, GS Virdi, W Zhang, JR Evans, AI Wernick, ZS Zanjani, PR Angelova, N Esteras, AY Vinokurov, K Morris, K Jeacock, L Tosatto, D Little, P Gissen, DJ Clarke, T Kunath, L Collinson, D Klenerman, AY Abramov, MH Horrocks, S Gandhi
Nat Neurosci
(2022)
25
(doi: 10.1038/s41593-022-01140-3)
Constructing a cost-efficient, high-throughput and high-quality single-molecule localization microscope for super-resolution imaging
JSH Danial, JYL Lam, Y Wu, M Woolley, E Dimou, MR Cheetham, D Emin, D Klenerman
Nature Protocols
(2022)
17
(doi: 10.1038/s41596-022-00730-6)
Yusuf Hamied Department of Chemistry
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